Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Chromosome segregation relies on kinetochores ...

Centre for Engineering Biology, Institute of Quantitative Biology, Biochemistry and Biotechnology, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3FF, U.K. Centre for ...

So et al. present an optimized protocol for single-nuclei RNA sequencing of adipose tissue in mice, ensuring better RNA quality and nuclei integrity. The authors use this protocol to explore the ...

(B) Devices linked to NIS-Elements. (C) NIS-Elements JOBS module configured for looped acquisition. (D) Optical configuration for simultaneous GCaMP6s/H2B-mCherry excitation. Suppl. Fig. 3. Location ...

Mean fluorescence intensity of the population was determined. pLV2-CMV-Rab5A-mCherry, pLV3-CMV-Rab7-mCherry, and pLV3-CMV-Rab11A-EGFP lentiviral constructs were used to express fusion protein ...

The structure, properties and dynamics of microtubules structures are tightly regulated by a plethora of proteins, including microtubule-associated proteins (MAPs), motor proteins and ...

Mechanobiology Institute Singapore, National University of Singapore, Singapore 117411, Singapore ...

Background Aberrant Wnt pathway activation is a key driver of colorectal cancer (CRC) and is essential to sustain tumour growth and progression. Although the downstream protein-coding target genes of ...