【导读】表观遗传重编程在癌症的进展中起着至关重要的作用，n6 -甲基腺苷(m6A)是真核生物中最常见的RNA修饰。本研究旨在探讨m6A调节因子构建的相关修饰模式，评价甲状腺癌的侵袭和迁移。10月8日，南华大学钟警/祖旭宇教授研究团队在期刊《Cell ...

2020年5月4日，中山大学附属孙逸仙纪念医院&广东省人民医院在Molecular Cancer (中科院一区 IF=27.7)期刊上在线发表题为 "circNFIB1 inhibits lymphangiogenesis and lymphatic ...

The regulation and remodeling of the tumor microenvironment (TME) are closely associated with how cancers typically progress ...

谈及癌症转移，一句话总结就是一个巴掌拍不响。这是纪念斯隆-凯特琳癌症中心（MSK）研究人员领导的一项新研究的主要发现之一：TGF-β和RAS信号通路共同促进了肺腺癌的扩散，而肺腺癌是全球癌症死亡的主要原因。近日，一篇发表在国际杂志 Cell 上题为 “TGF-β and RAS jointly unmask primed enhancers to drive metastasis” ...

In a paper published in MedComm - Future Medicine, a team of doctors developed a machine learning model to predict mesenteric lymph node metastasis in colorectal cancer patients by using preoperative ...

Viral infections are marked by a constant battle between the invading virus and the infected host.The outcome of this ...

A mouse xenograft model of DLBCL tumors was used to characterize the role of TNFAIP3 expression tumor growth. Tumors induced from cells with higher levels of TNFAIP3 had a lower volume compared with ...

Adjuvant chemotherapy was beneficial in children with unilateral retinoblastoma who underwent removal of the affected eye and ...

GlobalData’s report assesses the drugs in the Cathepsin L1 pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline.

决定依据《国家自然科学基金项目科研不端行为调查处理办法》第五十条第一项、第四项和第四十四条第四项，取消全成国家自然科学基金项目评审专家资格3年（2024年4月9日至2027年4月8日），取消全成国家自然科学基金项目申请和参与申请资格2年（2024年4月9日至2026年4月8日），给予全成通报批评。

In this important study, the authors used a zebrafish model and scRNAseq analysis to show that a subset of keratinocytes within melanoma microenvironment highly up-regulate Twist and undergo ...

A high density of tumor-associated macrophages (TAMs) is associated with poorer prognosis and survival in breast cancer patients. Recent studies have shown that lipid accumulation in TAMs can promote ...