Any lingering doubts over the feasibility of rolling out population-based cancer registries in low-income and middle-income countries ought to have been dispelled by the COVID-19 pandemic. Within ...

The blood–brain barrier is the biggest challenge to the development of drugs that target the CNS. Most capillary beds leak plasma contents between and across endothelial cells by way of window-like ...

For several decades, the prevalence of steatotic liver disease (SLD) has been steadily increasing.1 Alterations in hepatic ...

Heterogeneity in prevalence estimates identified across studies and regions indicates that more research is required to draw stronger conclusions about the scale of OCSEA. However, the findings of ...

Africa reached a pivotal milestone in its decades-long fight against malaria, a disease that has caused 94% of global cases and 95% of related deaths in Africa.1 Although global malaria mortality has ...

The fact that mental health was an overlooked and under-represented area of medicine was exactly what drew Dr Fahmy Hanna to it. While speaking to The Lancet Psychiatry, he said “I have a deep ...

Recurrent respiratory papillomatosis (RRP) is a disease of the upper airway presenting with exophytic wart-like lesions. These lesions are considered benign with less than a 1–5% chance of malignant ...

Asthma represents a substantial health burden in childhood globally, with minoritised populations being disproportionately impacted.1 Recent literature has increasingly linked social determinants of ...

Despite evidence that some people with excess adiposity have ill health due to obesity, obesity is generally considered a ...

A 4-year-old boy in a collision with a speeding motorcycle as he crossed the road was referred to our hospital from a ...

An international team has set out to answer one of the more vexing questions in paediatric medicine today—namely, are ...

There are 1·3 billion disabled people globally.1 Many of these individuals live positive lives and celebrate important achievements, but they also frequently face challenges to inclusion and achieving ...