The three-dimensional shape of a protein can be used to resolve deep, ancient evolutionary relationships in the tree of life, ...

In biology, the binding of cellular proteins to molecules called ligands produces myriad functions essential for life, ...

Federal science agencies have renewed and increased funding for a world-renowned digital archive of protein structures housed ...

The goal of this project is to build a database of protein sequences containing only gene families that have at least one sequence of an experimentally solved 3D structure available. To do so, we ...

Along with greater accuracy for the prediction of 3D protein structures ... “Experimental protein-structure prediction can take about the length of a PhD and cost hundreds of thousands of ...

Federal funds totaling $49.4 million will underwrite core operations supporting the digital archive of protein ...

QuantumFold integrates quantum circuits with classical deep learning to predict protein structures. Utilizing SidechainNet, it combines quantum feature encoding with LSTM layers for accurate ...

"We are now able to reconstruct 3D protein structures from two-dimensional ... Changes in the spatial structure of proteins can also be easily detected with ONE microscopy. In a collaboration ...

Proteins are fundamental to life. They are involved in virtually every process within our bodies, from catalyzing chemical ...

Protein higher-order structure (HOS) is key to biological function because the mechanisms of protein machinery are encoded in protein three-dimensional structures. Mass spectrometry (MS)-based protein ...

The amino acid sequence, encoded by its gene, determines a protein’s structure and function. Newly synthesized proteins can be modified by post-translational modification, altering its protein ...