The primary antibodies used, including P65, p-IκBα, IκBα, Pi3k, Akt, p-Pi3k, p-Akt, p38, caspase-3, cleaved caspase-3, Bax, Bcl-2, P53 and the loading control antibody β-actin levels were performed ...

Illumination’s musical animals are set to return with more animated tunes, as Sing 3 is currently on the way. Illumination is behind some of the best animated movies of our time, including ...

Malfunction of the p53 pathway is an almost universal hallmark of human tumours. [1,2] Somatic mutation of TP53 that results in the absence or dysfunction of p53 is one of the most common ...

Journal of Nuclear Medicine September 2024, jnumed.124.267736; DOI: https://doi.org/10.2967/jnumed.124.267736 ...

Venom: The Last Dance has dropped a final trailer, teasing Spider-Man star Rhys Ifans’s character. The star portrayed Dr Curt Connors/Lizard in The Amazing Spider-Man, though appears to be ...

Mitochondria-mediated apoptosis occurs in response to a wide range of death stimuli, including activation of tumor suppressor proteins (such as p53 ... caspase-9 holoenzyme is procaspase-3 ...

Cleaved caspase-3 protein levels were analysed and quantified densitometrically using the iBright ... In these pathways, nucleocytoplasmic translocation of mTOR triggers p53 phosphorylation, which in ...

Impairment of centrosomal nucleation in apical progenitors of the developing mouse brain induces p53-dependent apoptosis and causes non-lethal microcephaly. Whether disruption of non-centrosomal ...