p53 is a common denominator among human cancers. How was it discovered? What are the persistent questions about its function? Aa Aa Aa It seems nearly impossible for a normal cell to become a ...

Our lab has had a long-standing interest in the role and regulation of the p53 tumor suppressor. Mutations in the p53 gene (TP53) are often associated with aggressive tumor behavior and poor patient ...

The findings were recently published in Communications Chemistry. p53 is central to the body's defense against cancer, tasked with regulating the cell cycle and triggering the death of damaged ...

Cleavage of Caspase 3, PARP1 and HSP90, as well as increased Annexin V positivity ... Moreover, this combination is active against P53-negative and FLT3-ITD-positive cell lines. Enhanced activation of ...

When you purchase through links on our site, we may earn an affiliate commission. Here’s how it works. Little Nightmares 3 is set to arrive next year, following a delay. As such, there's still a ...

"A Quiet Place 3" is still in the works, and no we aren't talking about the spin-off prequel "A Quiet Place: Day One" that hit theaters over the summer. Set in a world invaded by terrifying alien ...

From season 3 is in full swing on MGM+, following on from that shock ending to season 2, which saw Tabitha (Catalina Sandino Moreno) seemingly fall to her death from the lighthouse – before ...