在《细胞》(Cell)发表了题为“肿瘤细胞中cenRNA的甲基化修饰稳定CNEPA蛋白结合从而保证着丝粒完整性”(m6A-modified cenRNA stabilizes CENPA to ensure centromere integrity in cancer cells)的研究论文。该研究首次揭示,肿瘤细胞中的cenRNA存在高频的m6A修饰,而经典的着丝粒 ...
A new single-cell omics model might help scientists better understand brain function. As reported in the September 24 Nature Neuroscience, researchers led by Kate Meyer, Duke University, Durham, North ...
The Single Cell Genomics Core provides comprehensive services for RNA and chromatin profiling on single or a small number of cells. The core is equipped with the 10x Genomics Chromium Platform, the ...
Inside every cell, inside every nucleus, your continued existence depends on an incredibly complicated dance. Proteins are ...
开发新型免疫靶点是提升免疫治疗效果的关键途径之一。徐瑞华教授研究团队在国际范围内率先提出了针对晚期胃癌的抗 CLDN18.2 治疗方案(免疫机制),为 CLDN18.2 阳性且 HER2 阴性的晚期胃癌患者开辟了新的治疗路径,显著改变了临床实践。此外 ...
How can a vast array of cell types, with distinct forms and functions, be produced from a single genome? With single-cell analysis technologies, researchers can start to understand the diversity of ...
Many eukaryotic cells exhibit shape changes, with one of the most fascinating examples being the unicellular ciliated eukaryote Lacrymaria, known for its extraordinary dynamic shape-shifting.
The advent of "mass cytometry" in 2009 allowed the simultaneous quantification of 50 proteins in single cells, and a more ...