The three-dimensional shape of a protein can be used to resolve deep, ancient evolutionary relationships in the tree of life, ...

In fact, each gene in cellular DNA contains the code for a unique protein structure. Not only are these proteins assembled with different amino acid sequences, but they also are held together by ...

The sequence of amino acids in the chain determines how the chain will fold up to make the protein, so different proteins have different three-dimensional shapes. The three-dimensional shape of a ...

Federal science agencies have renewed and increased funding for a world-renowned digital archive of protein structures housed ...

Protein structure predictions are bioinformatic analyses that produce predicted protein structures automatically using the protein amino acid sequence. Protein structures are important because ...

utilizing the Evoformer module to process the multi-sequence comparison data and combining with the 3D Equivariant structure ...

Proteins have four levels of structure: primary (amino acid sequence), secondary (local folding patterns like alpha helices and beta sheets), tertiary (overall 3D shape), and quaternary (assembly of ...

Researchers have now uncovered the 3D structure of the RNA enzyme SAMURI. Their study provides insights into the development of ribozymes and the evolution of catalytically active RNA.

No large RNA structure database exists that correlates sequence with 3D topology. Successful protein-centric methods like AlphaFold remain unavailable for RNA, creating a critical gap in ...