The Amyloid—Tangle Connection. Aβ aggregates (green) hyper-excite neurons in tau epicenters and connected regions, strengthening that connectivity. This pushes tau propagation from one region to ...
Immunostaining revealed that the fibril-derived protofibrils diffused rapidly through the brain into areas associated ... inert amyloid plaques into toxic protofibrils.
Immune cells in the brain called microglia can partially break down large amyloid plaques characteristic of Alzheimer's disease by latching on to them, forming a sort of external stomach and ...
Researchers from the University of Turku and Åbo Akademi University in Finland and the University of Wisconsin in the United States demonstrated that individuals who had childhood epilepsy have an ...
can oral bacteria cause a change in the brain cells?" The microglial cells the researchers studied are a type of white blood cell responsible for digesting amyloid plaque. Forsyth scientists found ...
Treatment was initiated when the mice were 10 months old, the age at which plaque deposition typically begins in this model. The brains of treated and untreated mice were compared 6 months later.
Higher levels of visceral fat were correlated with more amyloid plaque in the brains of cognitively ... were associated with high amyloid in the brain. The study showed effects of visceral fat ...