Creatine kinase M2 (CKMT2) plays a key role in mitochondrial dysfunction in type 2 diabetes, affecting energy metabolism in ...

Mitochondrial genome contributes polypeptide subunits to the five enzyme complexes that comprise the oxidative phosphorylation (OXPHOS) system within the inner mitochondrial membrane, the site of ...

研究显示，仅4个月的藏红花素治疗，可以提高老年小鼠细胞能量水平，显著改善了记忆力、探索性行为、协调性，并提高了大脑、心脏等重要器官中ATP和NAD + 水平，延缓了大脑衰老，并使平均寿命延长17.7%。

Tumor cells were classified into three metabolic states: OXPHOS+, OXPHOS-, and PPP+, with PPP+ cells showing increased proliferation, CD44 positivity, and a higher resistance to PD-1 blockade.

慢性肾脏病（CKD）是全球日益严重的公共卫生问题，全球范围内CKD的患病率已达到10%以上。预计到2050年，CKD将成为全球第5大死因。然而，无论CKD患者的病因如何（糖尿病、高血压、自身免疫性疾病等），肾小管间质和肾小球均会出现纤维化，是肾功能丧 ...

They assessed mitochondrial adenosine triphosphate (ATP) generation capability by analyzing oxidative phosphorylation (OXPHOS ...

Age-related post-transcriptional dysregulation most affects ECM and OXPHOS proteins. RNA-binding proteins (RBPs) modulate all aspects of RNA metabolism. Here the authors introduce a method named ...

基因分析显示，藏红花素通过上调与氧化磷酸化（OXPHOS）相关的基因来提升脑能量，且长期使用未引起氧化应激。上述结果表明，藏红花素有望用于 ...