This work presents a valuable finding on how the interplay between transcription factors SOX2 and OCT4 establishes the pluripotency network in early mouse embryos. Despite the high quality of the data ...

Researchers in Australia have found a whole new type of cell that fills a major hole in our understanding of how the mammal ...

Aging diminishes autophagy in short-lived model organisms. This study uncouples macroautophagy and mitophagy in the aging ...

A group of essential signaling molecules known as the Wnt pathway emerged early in the evolution of multicellular life.

Research from USC Stem Cell shows the critical role of Wnt signaling in nephron progenitor cells (NPCs) during kidney ...

This is an important piece of work that sheds light on our understanding of early lung development. There is solid evidence that there is a key new role for Svep1, which may be acting via FGF9. A more ...

This new genome-edited rat model of Becker muscular dystrophy (BMD) develops progressive heart failure with reduced ejection ...

African researchers are using Drosophila melanogaster fruit flies to advance studies of genetics, biomedicine, developmental biology, toxicology and more.