Our lab has had a long-standing interest in the role and regulation of the p53 tumor suppressor. Mutations in the p53 gene (TP53) are often associated with aggressive tumor behavior and poor patient ...

p53 is a common denominator among human cancers. How was it discovered? What are the persistent questions about its function? Aa Aa Aa It seems nearly impossible for a normal cell to become a ...

The ATM gene (mutated in the disease ataxia telangiectasia) activates the p53 tumor suppressor protein in response to DNA damage, explaining the higher incidence of cancer in AT patients.

The findings were recently published in Communications Chemistry. p53 is central to the body's defense against cancer, tasked with regulating the cell cycle and triggering the death of damaged ...

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The applications for modern day SoCs are becoming bulkier in size, which in turn requires a huge amount of storage. These storage solutions can be On-chip or Off-chip, depending on the system ...