B-cell activating factor receptor (BAFF-R) chimeric antigen receptor (CAR) T-cell therapy incited cytotoxic effects on both ...

Figure 1: The transcriptional control of late B-cell differentiation. Figure 2: Model of the interaction of BLIMP1 and IL-2 in T-cell differentiation. Although it is still early days in our ...

There are two main types of lymphocytes: B cell lymphocytes (B cells) and T cell lymphocytes (T cells). DLBCL affects B cells. B cells produce proteins called antibodies, which attach to bacteria ...

But subsequent reinfections often don't lead to the most severe outcomes—for very good reason. Upon first exposure to a ...

Recall germinal centers formed in response to a secondary infection generate a second line of defense, rebuffing memory B ...

CAR-T cells lose their potency CAR-T cell therapy is an emerging treatment for blood cancers, putting some B-cell lymphomas and leukemias into complete remission. However, this potential game ...

Human innate immune cells that “remember” previous stimulation could provide new insights into chronic inflammatory diseases.

"We really focus on one function of B-cells, which is the activation of CD8 T-cells," a specialized type of defensive immune cell which are tailored to fight specific pathogens. In the current ...

The CAR T-cells then recognise and attack the cancer cells. It is a possible treatment for children and adults with relapsed or refractory B cell acute lymphoblastic leukaemia (ALL). It is also a ...

The well-established existence of sex differences in immune responses, including immune responses driven by T cells, cuts ...

Unlike chimeric antigen receptor (CAR) T-cell therapies, which can identify surface antigens, TCR-T cell therapies like ...

Inmates at category B HMP Nottingham who dislike constant loud music, shouting, swearing and singing are being offered 'low ...