The Randomized Evaluation in PCI Linking Angiomax to Reduced Clinical Events (REPLACE)-2 trial showed that the direct thrombin inhibitor bivalirudin, with provisional glycoprotein (Gp) IIb/IIIa ...

Describes the nature of a clinical study. Types include: Observational study — observes people and measures outcomes without affecting results. Interventional study (clinical trial) — studies new ...

Topol pioneered the development of many routinely used medications, including tissue plasminogen activator, clopidogrel (Plavix), bivalirudin (Angiomax), and abciximab (ReoPro), and was the first ...

He has pioneered the development of many medications that are routinely used in medical practice including t-PA, Plavix, Angiomax and ReoPro and was the first physician to raise safety concerns on ...

Periprocedural Angiomax 16 mL (5 mg/mL) IV bolus (The Medicines Company, Parsippany, NJ), Angiomax IV drip (5 mg/mL), and 1,000 units of heparin were administered. The interventional procedure was ...

After more than 70 years of effective clinical use, heparin remains the most common anticoagulant in use and one of the most commonly prescribed drugs to hospitalized patients. However, the ...

With many questions about the management of patients undergoing transcarotid artery revascularization (TCAR) left unanswered, a multispecialty panel of carotid experts gathered to provide guidance on ...