Interleukin 10 - Wikipedia
Interleukin 10 (IL-10), also known as human cytokine synthesis inhibitory factor (CSIF), is an anti-inflammatory cytokine. In humans, interleukin 10 is encoded by the IL10 gene. [5] IL-10 signals through a receptor complex consisting of two IL-10 receptor-1 and two IL …
Ilyushin Il-10 - Wikipedia
The Ilyushin Il-10 (Cyrillic Илью́шин Ил-10, NATO reporting name: "Beast" [3]) is a Soviet ground attack aircraft developed at the end of World War II by the Ilyushin construction bureau. It was also license-built in Czechoslovakia by Avia as the Avia B-33.
Biology and therapeutic potential of interleukin-10 - PMC
The authors review the molecular mechanisms regulating IL-10 production and response and describe classic and novel functions of IL-10 in immune and non-immune cells. They further discuss the therapeutic potential of IL-10 in different diseases and ...
The regulation of IL-10 production by immune cells - Nature
2010年2月15日 · Interleukin-10 (IL-10), a cytokine with anti-inflammatory properties, has a central role in infection by limiting the immune response to pathogens and thereby preventing damage to the host.
Role of Interleukin 10 Transcriptional Regulation in Inflammation …
Interleukin 10 (IL-10) is a cytokine with potent anti-inflammatory properties that plays a central role in limiting host immune response to pathogens, thereby preventing damage to the host and maintaining normal tissue homeostasis. Dysregulation of ...
IL-10: The Master Regulator of Immunity to Infection
2008年5月1日 · IL-10 has emerged as a key immunoregulator during infection with viruses, bacteria, fungi, protozoa, and helminths (Table I), ameliorating the excessive Th1 and CD8 + T cell responses (typified by overproduction of IFN-γ and TNF-α) that are responsible for much of the immunopathology associated with infections including Toxoplasma gondii (1 ...
Interleukin-10: new perspectives on an old cytokine - PMC
IL-10 is a potent inhibitor of antigen presentation. It inhibits major histocompatibility complex class II expression as well as the upregulation of costimulatory molecules CD80 and CD86. IL-10 inhibits the differentiation of DCs from monocyte precursors, and it also inhibits DC maturation.
Interleukin 10 - an overview | ScienceDirect Topics
IL-10 is one of a family of antiinflammatory cytokines expressed in the skin. The importance of IL-10 in limiting inflammatory damage has been shown in studies of knock-out mice, which develop colitis and arthritis of the joints [86]. Treatment with viral IL-10 showed improved healing in full-thickness murine wound models [87].
Frontiers | The multifaceted nature of IL-10: regulation, role in ...
2023年5月24日 · IL-10 is a critical mediator of host innate and adaptive immunity. It has a multifaceted nature in stimulating or inhibiting crucial immune pathways. IL-10 as an immune modulator can decrease detrimental inflammation, inhibit …
The multifaceted nature of IL-10: regulation, role in ... - PubMed
2023年6月8日 · Interleukin-10 (IL-10) is a pleiotropic cytokine that has a fundamental role in modulating inflammation and in maintaining cell homeostasis. It primarily acts as an anti-inflammatory cytokine, protecting the body from an uncontrolled immune response, mostly through the Jak1/Tyk2 and STAT3 signaling …
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