Deep machine-learning speeds assessment of fruit fly heart …
2024年7月3日 · Drosophila — commonly known as fruit flies — are a valuable model for human heart pathophysiology, including cardiac aging and cardiomyopathy. However, a choke point in evaluating fruit fly hearts is the need for human intervention to measure the heart at moments of its largest expansion or its greatest contraction, measurements that allow ...
How Fruit Flies Stay Young at Heart | Smithsonian
2018年7月17日 · Today, scientists from the University of California, San Diego report that fruit flies engineered to maintain high levels of a heart-remodeling protein enjoy a much longer lifespan. Their...
Drosophila , Genetic Screens, and Cardiac Function - AHA/ASA …
2011年9月16日 · The fruit fly, Drosophila melanogaster, has been used to study genetics, development, and signaling for nearly a century, but only over the past few decades has this tremendous resource been the focus of cardiovascular research. Fly genetics offers sophisticated transgenic systems, molecularly defined genomic deficiencies, genome-wide ...
Deep machine-learning speeds assessment of fruit fly heart …
2024年7月3日 · Drosophila—commonly known as fruit flies—are a valuable model for human heart pathophysiology, including cardiac aging and cardiomyopathy. However, a choke point in evaluating fruit fly...
A heart that beats (almost) like our own - Iowa Now
2021年10月22日 · Biologists at the University of Iowa have unraveled how a “heart” in the fruit fly’s head functions. The researchers discovered the fly’s head-heart beats much like a human’s: Its rhythmic pulses are automatically generated by …
Non-invasive red-light optogenetic control of Drosophila cardiac ...
2020年6月29日 · The red LED (~617 nm) optically stimulates the fly heart. Compared with the maximum response wavelengths of ReaChR and NpHR (~590 nm and ~580 nm, respectively), LED light at ~617 nm...
A Drosophila heart optical coherence microscopy dataset for …
2023年12月9日 · The heart of the fruit fly, Drosophila melanogaster, is a particularly suitable model for cardiac studies. Optical coherence microscopy (OCM) captures in vivo cross-sectional videos of the...
A new method for detection and quantification of heartbeat …
A number of methods have been developed to detect and quantify heart rate in fruit flies. Manual counting of heart beats visualized through the cuticle of intact pupae and flies has been used previously, but is not practical or accurate for long periods of time or during periods of high-frequency beating.
Dual color optogenetic tool enables heart arrest, bradycardic, and ...
2024年8月27日 · In order to facilitate cardiovascular research to develop non-invasive optical heart pacing methods, we have generated a double-transgenic Drosophila melanogaster (fruit fly) model suitable...
Scientists Identify Genetic Cues for a Big Heart - Duke Today
2015年2月3日 · Unlike the human heart with its complex array of four chambers, four valves, and multiple vessels, the fruit fly heart is simply a linear tube composed of a single layer of 104 heart cells. Wolf and his colleagues were able to visualize enlargement of the tiny beating heart with a method called optical coherence tomography that is something ...
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