Milling Medium‐Free Suzuki Coupling by Direct Mechanocatalysis: …
2023年7月28日 · The addition of the right amount of LAG, is critical for reaching an optimal rheology and conversion of substrates (η-sweet spot). 4 Furthermore, we extend this concept of medium-free milling to a resonant acoustic mixer (RAM), which currently emerges as a promising technology for mechanochemistry (co-crystallization, 5 functional materials, 6 ...
Direct mechanocatalysis by resonant acoustic mixing (RAM)
2023年5月18日 · We demonstrate the use of a metal surface to directly catalyse copper-catalysed alkyne–azide click-coupling (CuAAC) reactions under the conditions of Resonant Acoustic Mixing (RAM) – a recently introduced and scalable mechanochemical methodology that uniquely eliminates the need for bulk solvent, as well as Most popular 2023 organic ...
Direct mechanocatalysis by resonant acoustic mixing (RAM)
2023年7月7日 · We demonstrate a simple strategy to use a metal surface to directly catalyse mechanochemical reactions by Resonant Acoustic Mixing (RAM), a scalable mechanochemical methodology that uniquely eliminates the need for grinding media or bulk solvent.
2024年6月4日 · Mechanochemistry is the iniiaion of chemical reacions by mechanical forces such as grinding, shearing, milling, or mixing. Tradiional mechanochemistry processing methodologies vary from hand grinding (i.e., mortar and pestle) to shaker and planetary mills for …
Ball-free mechanochemistry: in situ real-time monitoring of ...
2018年3月29日 · Resonant acoustic mixing (RAM) is a new technology designed for intensive mixing of powders that offers the capability to process powders with minimal damage to particles. This feature is particularly important for mixing impact-sensitive materials such as explosives and propellants. While the RAM technique
Halogen-bonded cocrystals via resonant acoustic mixing
Resonant acoustic mixing is a relatively gentle mechanochemical technology that employs pressure waves to induce chemical and morphological transformations. We report here on the production of eleven halogen-bonded (XB) cocrystalline architectures via neat and liquid-assisted resonant acoustic mixing (RAM).
Operando acoustic analysis: a valuable method for investigating ...
We present a new operando approach for following reactions taking place in mechanochemistry, relying on the analysis of the evolution of the sound during milling. We show that differences in sound can be directly correlated to (physico)chemical changes in the reactor, making this technique highly attractive and complementary to others for ...
Direct mechanocatalysis using Resonant Acoustic Mixing (RAM)
2023年3月8日 · We demonstrate the first example of direct mechanocatalysis by Resonant Acoustic Mixing (RAM), an emerging mechanochemical methodology that eliminates the need for bulk solvent and milling media.
Metal-Catalyzed Organic Reactions by Resonant Acoustic Mixing
2022年1月20日 · We demonstrate catalytic organic synthesis by Resonant Acoustic Mixing (RAM): a mechanochemical methodology that does not require bulk solvent or milling media.
In light of the great interest in mechanochemistry, several research groups have thus strongly focused their attention on developing in situ as well as operando analytical methods in order to monitor reactions and observe evolutions in the structure, crystallinity and/or texture of compounds involved