HDBuzz - Huntington’s disease research news.
4 天之前 · Beta-blockers associated with delayed onset and decreased progression of Huntington’s disease. A well-studied, widely used class of drugs for heart health may have benefits for Huntington’s disease.
2024: Year in Review - HDBuzz - Huntington’s disease research news.
4 天之前 · As we wave goodbye to 2024, the HDBuzz team reflects on a year marked by significant progress, challenges, and hope. From breakthroughs at the lab bench, advancements in drug development, and both road bumps and triumphs in clinical trials, we have gained new insights into the workings of Huntington’s disease (HD), and made great strides towards finding medicines which might slow or halt ...
2024 HDBuzz Prize: A NEAT new dance partner for Huntingtin
2024年12月23日 · We’re proud to announce AJ Keefe as our last HDBuzz Prize winner of 2024! Our cells are an intricate choreography between various molecular dancers. Knowing who moves well with whom, and how that changes with disease, could help advance drugs for HD.
Moving into the Fast Lane: uniQure and the FDA Are on the Same …
On December 10, 2024 we received a regulatory update from uniQure about their drug, AMT-130, that they’re advancing through the clinic for Huntington’s disease (HD). On the call, uniQure announced alignment with the FDA on key elements to …
2024 HDBuzz Prize: Thinking beyond therapies - it’s time to …
2024年10月28日 · We're proud to announce Dr. Zanna Voysey as a 2024 HDBuzz Prize winner! She shares a new study that details racial disparities in HD care and research. Addressing this could improve the lives of people living with HD in the here-and-now.
Going boldly: First person treated in Phase 1 clinical trial by …
On December 3, 2024 a study site gave word that the very first person received a new drug, called ALN-HTT02, as part of a Phase 1 trial aiming to treat Huntington’s disease (HD). Going boldly as the first human ever to receive this drug, they’re charting a course that we …
2024 HDBuzz Prize: Beyond nerve cells – who are the other players …
2024年11月25日 · We're proud to announce Jenny Lange as a 2024 HDBuzz Prize winner! Our brains are made up of many types of cells that play different roles in the changes caused by HD. This study dives into a star-shaped cell called astrocytes and their role in HD.
Interim update from Vico Therapeutics on their CAG-targeting …
2024年12月9日 · Vico Therapeutics recently presented at several conferences to share an interim update on their Phase 1/2a clinical trial testing their drug called VO659, which targets the repeating C-A-Gs in people with Huntington’s disease (HD). These data suggest that VO659 may be able to reduce levels of the toxic HD protein in the small group of participants tested so far and gives insights into safety.
Huntington's Disease Therapeutics Conference 2024 - Day 3
2024年3月7日 · Glossary; huntingtin protein The protein produced by the HD gene.; clinical trial Very carefully planned experiments designed to answer specific questions about how a drug affects human beings ; therapeutics treatments ; juvenile HD Huntington's disease where symptoms begin before the age of 20.; CAG repeat The stretch of DNA at the beginning of the HD gene, which contains the sequence CAG ...
2024 HDBuzz Prize: Social Skills - The Hidden Gem in Improving …
2024年11月4日 · We're proud to announce Molly Gracey as a 2024 HDBuzz Prize winner! Could social skills be the secret ingredient to a better quality of life in people with #HuntingtonsDisease? Clues suggest these 'hidden gems' impact #QualityOfLife in HD.