Transgenerational epigenetic inheritance - Wikipedia
Transgenerational epigenetic inheritance is the transmission of epigenetic markers and modifications from one generation to multiple subsequent generations without altering the primary structure of DNA. [1]
Molecular mechanisms of transgenerational epigenetic inheritance …
2022年1月4日 · In this Review, Fitz-James and Cavalli discuss the diverse and often multilayered mechanisms by which transgenerational epigenetic inheritance can occur in different species.
Transgenerational Epigenetic Inheritance - PubMed
2018年11月23日 · Here, we review major model systems for transgenerational epigenetic inheritance via the germline in multicellular organisms. In addition to surveying examples of epivariation that may arise stochastically or in response to unknown stimuli, we also discuss the induction of heritable epigenetic changes by genetic or environmental perturbations.
A critical view on transgenerational epigenetic inheritance in …
2018年7月30日 · In this comment, I discuss the phenomenon of transgenerational epigenetic inheritance and the difficulty of providing conclusive proof for it in experimental and observational studies.
Epigenetic Inheritance: Concepts, Mechanisms and Perspectives
According to the classical definition of transgenerational epigenetic inheritance, environmental triggers that hit pregnant female individuals (F0) can affect “directly” not only the first new generation (F1), but also its germ cells that represent the second generation (F2).
Intergenerational and transgenerational epigenetic inheritance …
2019年1月2日 · Examples of true transgenerational epigenetic inheritance (TEI) induced by parental genotype, physiology or environment have been increasingly numerous in model animals.
Transgenerational Epigenetic Inheritance - Annual Reviews
Here, we review major model systems for transgenerational epigenetic inheritance via the germline in multicellular organisms. In addition to surveying examples of epivariation that may arise stochastically or in response to unknown stimuli, we also discuss the induction of heritable epigenetic changes by genetic or environmental perturbations.
Transgenerational Epigenetic Inheritance: Myths and …
DNA methylation is the best-studied epigenetic mechanism for transgenerational inheritance but is neither universal nor as stable as once thought, with dynamic changes during development and in the germline.
Mechanisms of transgenerational epigenetic inheritance: …
2023年4月1日 · Specifically, when environmentally modulated epigenetic information is passed through gametes and elicits a phenotypic output in the progeny of exposed organisms, we refer to this phenomenon as intergenerational epigenetic inheritance (IEI, from parental to …
Transgenerational Epigenetic Inheritance: Prevalence, …
This review describes new developments in the study of transgenerational epigenetic inheritance, a component of epigenetics. We start by examining the basic concepts of the field and the mechanisms that underlie epigenetic inheritance.