- Medication for pain relief Over-the-counter medications may help ease UTI symptoms. For example: Acetaminophen may help to reduce pain and fever. Phenazopyridine (Pyridium, AZO) helps to alleviate pain and burning. Methenamine/Sodium salicylate/Benzoic acid (Cystex) may help to ease pain and inflammation.www.healthline.com/health/medicine-for-urinary-tract-infection
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