Dynein - Wikipedia
Dyneins are a family of cytoskeletal motor proteins that move along microtubules in cells. They convert the chemical energy stored in ATP to mechanical work. Dynein transports various cellular cargos, provides forces and displacements important in mitosis, and drives the beat of eukaryotic cilia and flagella.
Functions and mechanics of dynein motor proteins - PMC
Fuelled by ATP hydrolysis, dyneins generate force and movement on microtubules in a wealth of biological processes, including ciliary beating, cell division and intracellular transport. The large mass and complexity of dynein motors have made elucidating their mechanisms a sizable task.
The cytoplasmic dynein transport machinery and its many cargoes …
2018年4月16日 · Cytoplasmic dynein is a minus-end-directed microtubule-based motor that transports a wide range of cargoes, including organelles, RNAs, protein complexes and viruses.
Dyneins: Current Biology - Cell Press
2023年12月18日 · In this primer, we first highlight the structure, mechanism, and regulation of dynein-1, which is the best-characterized member of the dynein motor family, and then describe the unique features and cellular roles of other dyneins.
What is Dynein? - News-Medical.net
2019年2月26日 · Dynein performs a number of cytoplasmic cellular functions. It serves as the power behind the transport of membrane-bound tubules and vesicles in conjunction with their occupant molecules.
Dynein - an overview | ScienceDirect Topics
Dynein is a large cytoskeletal motor protein that belongs to the AAA + (ATPases associated with diverse cellular activities) superfamily. While dynein has had a rich history of cellular research, its molecular mechanism of motility remains poorly understood.
Structure of dynein–dynactin on microtubules shows tandem …
2022年9月7日 · The structure of the complete dynein–dynactin complex and its interaction with microtubules and cargo adaptors are visualized using cryo-electron microscopy.
Dynein Motor Protein - YouTube
Dyneins are a family of cytoskeletal motor proteins that move along microtubules in cells. They convert the chemical energy stored in ATP to mechanical work....
The ciliary inner dynein arm, I1 dynein, is assembled in the …
To determine mechanisms of assembly of ciliary dyneins, we focused on the Chlamydomonas inner dynein arm, I1 dynein, also known as dynein f. I1 dynein assembles in the cytoplasm as a 20S complex similar to the 20S I1 dynein complex isolated from the axoneme.
Crystal clear insights into how the dynein motor moves
2013年2月1日 · Dyneins are motor proteins that move along microtubules. They have many roles in the cell. They drive the beating of cilia and flagella, move cargos in the cytoplasm and function in the mitotic spindle. Dyneins are large and complex protein machines. Until recently, the way they move was poorly understood.