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BACKGROUND: Heart failure with preserved ejection fraction (HFpEF) is a major health concern. Pathological stimuli and interactions between cardiac fibroblasts (CFs) and other cell types may lead to ...

Myocardial infarction (MI) is a complex disease caused by both lifestyle and genetic factors. This study aims to investigate the predictive value of genetic risk, in addition to traditional ...

Heart failure with preserved ejection fraction (HFpEF) is a major public health problem characterized by multiple simultaneous comorbidities whose specific contribution is challenging to disentangle ...

State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union ...

Department of Neurosurgery and Neurology (Y.X., B.S., C.L., C.W., J.D., R.M., F.Y., J.C., X.J.), Xuanwu Hospital, Capital Medical University. China-America Institute ...

Mitochondrial dysfunction is a key factor in the development of atherogenesis. METTL4 (methyltransferase-like protein 4) mediates N6- methyldeoxyadenosine (6mA) of mammalian mitochondrial DNA (mtDNA).

The cardiovascular impact of cannabis use is incompletely understood. Although evidence links chronic use to an increased risk of disease and adverse cardiovascular events, few studies have ...

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Declining cardiovascular mortality rates have been well-documented, yet temporal trends of sudden cardiac death (SCD) in young individuals remain unclear. We provide contemporary nationwide estimates ...

Almost everyone who first sees moving heart walls, valves, and flows by echocardiography experiences fascination and wonder. Echocardiography is unique among cardiac imaging modalities because It ...

The progress in recognizing the breadth of human genetic diversity provides new understanding for mechanisms and potential treatments for cardiovascular diseases (CVDs). The first human genome was ...