The San Francisco 49ers are set to host the Detroit Lions at Levi's Stadium in Santa Clara, California, on Monday, December ...

San Francisco 49ers head coach Kyle Shanahan addressed reporters on Saturday following the team's final practice before their ...

The San Francisco 49ers entered Sunday's matchup against the Miami Dolphins without two key offensive contributors: running ...

San Francisco 49ers head coach Kyle Shanahan spoke with reporters after Saturday's practice as the team prepares for its Week ...

Head coach Kyle Shanahan offered an update on Saturday regarding the recovery of San Francisco 49ers wide receiver Brandon ...

The NFL's much-discussed new rule against hip-drop tackles has only produced one penalty flag this season, against Carolina's ...

The San Francisco 49ers face slim odds of landing a top-nine pick in the 2025 NFL Draft. The Carolina Panthers and New York ...

Tight end George Kittle is known for being one of the most upbeat and positive personalities in the San Francisco 49ers ...

The 49ers will have running back Isaac Guerendo for Monday Night Football. Guerendo, who missed last week's game with a ...

The 49ers are set to head into their "Monday Night Football" contest with the Detroit Lions a little worse for the wear, ...

San Francisco 49ers running back Isaac Guerendo is expected to return from foot and hamstring injuries and play Monday, a ...

Last year, the Lions were 30 minutes from their first Super Bowl apperance. But their 17-point lead evaporated, and their ...