Studying these diverse modes of mRNA splicing, which produces distinct ... scientists' understanding of the CaMK IV-mediated signaling pathway leading to skipping of the STREX exon (Shin & Manley ...

Prostate cancer is the second most common cancer in men worldwide. Despite medical advances in recent years, this type of ...

8 By delivering dsRNA that are complementary to a target gene’s mRNA, researchers redirect the RNAi pathway from its canonical functions to cleave the target and prevent its translation. Unlike gene ...

A cell signaling mechanism of fundamental importance to animal development is the Notch pathway (Figure 1). It may be safely said that Notch signaling is required, in some reasonably direct fashion, ...

The study demonstrates that activating the vitamin D receptor (VDR) with calcitriol suppresses cell proliferation in ...

They interfered with signaling pathways, including those that would ... This foundational research is one of the reasons that ...

Liu designed a novel shRNA targeting lipin1 mRNA and encapsulated it in an ... within neurons but also activates mTOR and ...