With their talismanic QB out for their Week 18 clash with the Cardinals, the 49ers will sit Brock Purdy for their closer as they look ahead to next season.
Sports reporters who cover the Los Angeles Rams and Chargers, Seattle Seahawks, San Francisco 49ers, and Arizona Cardinals come together to break down how the NFC West is shaping up this season.
Here are our experts' predictions for this NFC West matchup. The Cardinals are favorites to defeat the 49ers, according to the BetMGM NFL odds. Not interested in this game? Check out expert picks ...
The final week of NFL regular season action is here. The San Francisco 49ers and Arizona Cardinals will face off in an NFC West showdown. The 49ers are 6-10, while the Cardinals are 7-9.