Convincingly, the mechanism by which neuroblastoma-secreted GDNF increases Claudin-5 and VE-cadherin is described. To substantiate the role of GDNF in vivo, authors demonstrated that knock-down of ...

Methods Skin sections were immunostained for endothelial CD31 or vascular endothelial (VE)-cadherin in combination with α-smooth muscle actin (α-SMA) myofibroblast marker. Dermal microvascular ECs ...

氧气和代谢物的有效分配对于胚胎发育和生长以及组织稳态至关重要。这是通过内皮细胞形成并维持封闭的管状血管循环网络来实现的。内皮细胞是高度可塑性的细胞，能够在血管发育的不同阶段产生不同的动态反应，以构建组织特异性模式和形态的血管网络。在这篇综述中，我们讨 ...

You've Been Gnomed is a computer animation of a gnome mythical creature named Noggin Clontith, who taunts the viewer at the end of the clip by saying "You've been gnomed!" On May 29th, 2008, the ...

Researchers at University Hospital of the Technical University of Munich have found that cannabidiol (CBD) may help protect lung endothelial cells from the harmful side effects of radiation, which ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Regulation of neutrophil activation plays a ...

Mitochondrial dysfunction, characterized by impaired lipid metabolism and heightened reactive oxygen species generation, results in lipid peroxidation and ferroptosis. Ferroptosis is an inflammatory ...

1 Institute for Neuro-Immune Medicine, Dr. Kiran C. Patel College of Osteopathic Medicine, Nova Southeastern University, Ft. Lauderdale, FL, United States 2 Department of Pharmacological and ...

That meeting has been on my mind quite a bit over the last few weeks. While much of the game industry has been on edge in anticipation of whatever the follow-up to the Switch will be, Nintendo has ...