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Researchers found that inhibiting the enzyme TYK2 may reduce the harmful accumulation of tau protein in Alzheimer’s disease, ...
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TYK2 enzyme changes tau protein from a protective role to a harmful one, contributing to Alzheimer’s disease progression.
The team tested the effect of partially reducing TYK2 in two mouse models and found that this was sufficient to reduce tau levels and mitigate its accumulation. "Although much work is needed, our ...