Immunotherapy is based on harnessing a person's own immune system to attack cancer cells. However, patients with certain tumors do not respond to these therapies and it remains unclear why.

Immunotherapy, cancer treatments that alter the immune system, making it better apt to fight tumor cells, have provided novel ...

Based on early studies, it was hypothesized that expression of Fas ligand (FasL) by tumor cells enabled them to counterattack the immune system, and that transplant rejection could be prevented by ...

However, as tumors evolve, they exploit the TIME to ... thereby influencing processes like immune escape, angiogenesis, and metastasis. HCC is particularly adept at manipulating the TIME via ...

Immunotherapy is a treatment that strengthens the ability of the patient’s own immune system to detect and destroy cancer. Cancer cells often have mutations that allow them to escape the immune system ...

Researchers at Karolinska Institutet and the Astrid Lindgren Children's Hospital in Sweden have determined how children's ...

A group of immune proteins called the inflammasome can help prevent blood stem cells from becoming malignant by removing certain receptors from their surfaces and blocking cancer gene activity, ...

A research team at the Medical University of Vienna led by Maria Sibilia has investigated a new combination therapy against cancer. This therapy employs systemic administration of the tissue hormone ...

Cancer is a multifactorial disease that affects millions of individuals worldwide and has a profound impact on public health. The heterogeneity of solid ...

(Top right) Antigen escape: tumor cells can downregulate or lose the ... This strategy fosters a proinflammatory environment within tumor tissue, enhancing immune activation and amplifying antitumor ...