EGFR-positive lung cancer is a type of lung cancer with an epidermal growth factor receptor (EGFR) mutation. In the United States, around 10% to 15% of lung cancers are EGFR-positive. Most of these ...

Epidermal growth factor receptor (EGFR) is a protein on the surface of your cells that helps them grow. When the gene that codes for EGFR has a mutation, it affects the way this protein works ...

EaStCHEM School of Chemistry, The University of Edinburgh, Edinburgh EH9 3FJ, U.K. Centre for Inflammation Research, The University of Edinburgh, Edinburgh EH16 4UU, U.K. IRR Chemistry Hub, Institute ...

In addition, SHANK2 R240 methylation activated endosomal FAK/cortactin signals in vitro and in vivo. Consistently, all the levels of PRMT7, methylated SHANK2, FAK Y397 phosphorylation and cortactin ...

The neural crest is a dynamic progenitor cell population that arises at the border of neural and non-neural ectoderm. The inductive roles of FGF, Wnt, and BMP at the neural plate border are well ...

Reverse-phase protein microarray was used to evaluate protein levels and activation/phosphorylation status of HER family (EGFR, HER2 and HER3) and downstream signaling molecules. The analysis was ...