Over the last 2 decades, significant progress has been made in our understanding of the genomics, tumor immune microenvironment, and immunogenicity of malignant melanoma. Historically, the prognosis ...
The majority of patients had received prior PD-(L)1 based therapy. Encouraging signals of anti-cancer activity were observed ... 75-year-old patient with BRAF mutant metastatic cutaneous melanoma who ...
The clinical trials are sponsored by IO Biotech and conducted in collaboration with Merck, which is supplying pembrolizumab. IO Biotech maintains global commercial rights to IO102-IO103. KEYTRUDA® is ...
By Ayako Wakatsuki Pedersen, Ph.D., Senior Vice President of Translational Research at IO Biotech | Making the tumor microenvironment hostile to cancer cells and immune-suppressive cells may transform ...
We recently presented encouraging efficacy and safety data at ESMO on NUC-7738 plus pembrolizumab in patients with metastatic melanoma who were refractory or resistant to PD-1 inhibitors. We are ...
Researchers reviewed 293 studies encompassing 305,879 adults with cancer who were treated with anti-CTLA4 or anti-PD-(L)1 therapy alone or in combination and had information available on ...