BACKPACKOriginal ArticleTitle:Dual-function natural products: Farnesoid X receptor agonist/inflammation inhibitor for ...

Osthole can regulate NLRP3 inflammasome by activating AMPK ... Wnt/β-catenin, PI3K-AKT, TGF-β/Smad, MAPKs, Keap1/Nrf2, Notch and NF-κB pathways. The review provides new evidence for the discovery of ...

During cerebral ischemia, reactive oxygen species produced in the ischemic brain induce oxidative stress and inflammatory responses. Nrf2 is a transcription factor responsible for regulating cellular ...

Marmesin and Marmelosin Interact with the Heparan Sulfatase-2 Active Site: Potential Mechanism for Phytochemicals from Bael Fruit Extract as Antitumor Therapeutics. Investigation of the Effects of ...

Ginsenoside AD-2 Ameliorating Lipopolysaccharide-Induced Activation in HSC-T6 Cells and Carbon Tetrachloride-Induced Hepatic Fibrosis in Mice via Regulation of VD-VDR Axis.

These experiments used the 4-octyl modification to ensure that itaconate could get into the cells. Itaconate’s anti-inflammatory action is thought to work by activating a signaling process in cells ...