NFAT1–4 are regulated by the calcium-sensitive phosphatase calcineurin ... are not only thought to reinforce the idea that the NFAT pathway is a key signalling axis in cancer progression ...

Anjana Rao recounts the contributions of two talented and productive postdoctoral fellows who purified and characterized the transcription factor NFAT. You have full access to this article via ...

This makes calcineurin unavailable for the dephosphorylation of nuclear factor of activated T cells (NFAT), which means that NFAT cannot move into the nucleus, it cannot bind to cytokine promoters ...