Among them, NADPH oxidases (NOX), including NOX1-5, are major sources of ROS that mediate redox signaling in both physiological and pathological processes, including fibrosis, hypertrophy, and ...

We hypothesise that HCQ might target endosomal NADPH oxidase (NOX), which is involved in the signal transduction of cytokines as well as antiphospholipid antibodies (aPL). Methods For in vitro ...

Dysfunctional endothelium displays activation of vascular NADPH oxidase, uncoupling of endothelial nitric oxide synthase, increased expression of endothelin 1, a changed balance between the ...

Alpha- and beta-blockers reduce oxidative stress and inflammation caused by aircraft noise but fail to prevent hypertension, ...

From research, the charity says that it has 'established that an enzyme called NADPH oxidase, which occurs naturally in the body but is increased in disease, plays an important role in causing heart ...

Soursop is a fruit that goes by many names, including guanabana, paw-paw, sirsak, and graviola. It's the fruit of the small evergreen tropical tree native to Central and tropical South America ...

Expert Rev Clin Pharmacol. 2008;1(6):749-757. Current drugs available for the treatment of primary arterial hypertension (PAH) do not markedly improve survival and novel therapeutic strategies are ...

Structural, functional, and molecular‐level changes in the aging heart are influenced by a dynamic interplay between immune signaling and cellular metabolism that is referred to as immunometabolism.

Hubei Key Laboratory of Genetic Regulation & Integrative Biology, Key Laboratory of Pesticide and Chemical Biology of Ministry of Education, School of Life Sciences, Central China Normal University, ...

1 The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine, Shenzhen, Guangdong, China 2 Shenzhen Clinical College of Integrated Chinese and Western Medicine, Guangzhou ...