Headache Medicine: What Should You Take? Medicines can help you manage, prevent, or end headache pain. There are many different treatment options available. Some medicines relieve headache pain ...

Among her must-haves are combo she takes “when I’m down bad” and a “more potent nasal decongestant” than DayQuil.

The study found that soreness, headaches, and fatigue were the most common side effects of the treatment but that the did not last longer than 2 hours. There were no serious side effects reported.