In this 6-week, double-blind trial, 585 patients were randomized to losartan/ hydrochlorothiazide or losartan as monotherapy and titrated as needed at 2-week intervals to reach goal blood pressure ...

The angiotensin II type 1 receptor antagonist (angio-tensin receptor blocker [ARB]) losartan has been shown in the LIFE (Losartan Intervention for Endpoint Reduction in Hypertension) study to ...

Abstract We investigated the effects of angiotensin II (Ang II) type 1 receptor blockade with losartan on the renin-angiotensin-aldosterone system in hypertensive patients (supine diastolic blood ...

A daily polypill was estimated to be cost-effective for primary CVD prevention among U.S. adults living in historically ...

Amlodipine and turmeric interaction studies ... If the damage is severe, additional treatment may be necessary. Cozaar (losartan) is a medication that treats high blood pressure and certain ...

St. John’s wort is an herb used in dietary supplements to relieve symptoms of depression. Research shows that St. John’s wort ...

Research is unclear on whether apple cider vinegar can help lower blood pressure. Your healthcare team can best advise you on using any natural remedies or alternative treatments. Apple cider ...

Soon after, other combinations were being tested in the clinic, such as ACE inhibitors and diurectics (lisinopril and hydrochlorothiazide); ARBs and diuretics (losartan or valsartan and ...

Division of Nephrology, Department of Medicine, Duke University School of Medicine, Durham, NC (S.S., S.N., M.A.S.).