After 6 weeks, significantly more patients reached goal BP after one titration step of combination therapy vs ... 4, and 6. Losartan/HCTZ: Week 2, n=393; Week 4, n=392; Week 6, n=368; losartan ...

Abstract We investigated the effects of angiotensin II (Ang II) type 1 receptor blockade with losartan on the renin-angiotensin-aldosterone system in hypertensive patients (supine diastolic blood ...

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Both the mean SiDBP and SiSBP at baseline were similar between the treatment groups, 171.0/113.4 mm Hg for the losartan/HCTZ combination arm and 170.5/113.3 mm Hg for the losartan monotherapy arm.

New Delhi: Considering the request for bioequivalence (BE) and Phase III clinical trial (CT) waiver, the Subject Expert Committee (SEC) functional under the Central Drug Standard Control Organisation ...

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