Chronic migraine becomes “refractory” when preventive treatments don’t work to reduce the frequency of episodes. Treatment may include complementary therapies like neuromodulation.
The vast majority of migraines and other primary headaches can be treated safely at home with OTC or prescription medications. However, some migraines and headaches can turn into chronic conditions.
For a report published in July 2018, the Institute for Clinical and Economic Review (ICER) reviewed 11 clinical trials of CGRP inhibitors for preventing chronic migraine and eight trials of CGRP ...