Colorectal cancer (CRC ... supporting a polyclonal origin model. Researchers, utilizing a base editor-enabled DNA barcoding system, meticulously mapped the single-cell phylogenies in mouse ...

“The study looks at an important area of colorectal cancer biology using rigorous mouse models. And it's attempting to address two pathways by which colon cancer initiates,” said Nilay Sethi, a cancer ...

Using a computational “digital twin” model, researchers mapped the gene networks controlling cell differentiation. They ...

These results were consistent across mouse models of colon cancer the researchers studied, along with organoids -- lab-grown miniature organs -- derived from human colon cancer patients.

Colorectal cancer predominantly affects people ... "At the end of the day, it's impractical to apply our care models for ...