Chronic migraine becomes “refractory” when preventive treatments don’t work to reduce the frequency of episodes. Treatment may include complementary therapies like neuromodulation.
[92] Onabotulinum toxin-A is approved for headache prophylaxis in adults with chronic migraine and has approximately the same rate of improvement. Side effects of PAM drugs should be reviewed ...
People with chronic migraine experience at least ... Lipton et al, Early Improvements With Atogepant for the Preventive Treatment of Migraine, Neurology (2024). DOI: 10.1212/WNL.
Chronic migraine is a severe neurological disorder impacting physical and mental health, causing frequent headaches and affecting daily life. It limits social activities, reduces work efficiency ...