This requires both extravasation of cancer cells from the tumor and ... they are critical steps in the metastatic process that impose significant selective pressure on tumor cells.

Reduced mTOR and amino acid signaling triggers autophagy for cancer cell survival. Autophagic death is attenuated by chemokines in circulation, surviving signaling and possibly other mechanisms.

Cancer metastasis—the spread of cancer to other organs—is the leading cause of death among cancer patients. Researchers have ...

Cancer metastasis—the spread of cancer to other organs—is the leading cause of death among cancer patients. Researchers have now uncovered a “genetic signature” of 177 genes shared across multiple ...

Osteosarcoma is a type of aggressive bone cancer that most commonly affects children and young adults between the ages of 10 ...

Tumor cells circulating in the blood are the 'germ cells' of breast cancer metastases. They are very rare and could not be propagated in the culture dish until now, which made research into therapy ...

Tumor cells circulating in the blood are the “germ cells” of breast cancer metastases. They are very rare and could not be propagated in the culture dish until now, which made research into therapy ...

An amino acid appears to make the lungs more likely to have cancer spread to them from elsewhere in the body Aspartate ...

Tumor cells circulating in the blood are the "germ cells" of breast cancer metastases. They are very rare and could not be propagated in the culture dish until now, which made research into therapy ...

Osteosarcoma is the most common primary cancer of the bone, with a peak incidence in children and young adults. Researchers ...

New research reveals that ER+ breast cancer cells acquire aggressive characteristics through direct contact with bone marrow ...