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5 天
《科学》重磅:让T细胞“不知疲倦”持续抗癌的秘诀,竟藏在调控 ...
*仅供医学专业人士阅读参考把肿瘤微环境内因抗原慢性刺激转入耗竭状态的CD8+T细胞“叫醒”,让它们重新活化为效应CD8+T细胞,是PD-1/L1抑制剂为代表的现有免疫治疗起效的关键,但实话实说,激活处在耗竭状态的CD8+T细胞,在奇点糕眼里总觉得有点 ...
6 天
《自然》:最适合“双免疫方案”的肺癌患者群体可能被找到了!
*仅供医学专业人士阅读参考在目前已经获批的各种免疫联合治疗方案里,PD-1/L1抑制剂和CTLA-4抑制剂组成的“双免疫方案”,经常给奇点糕一种双刃剑的感觉,一方面它们确实取得了不少关键临床研究的成功,对非小细胞肺癌(NSCLC)、肝癌等常见实体瘤有 ...
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