First, the structure and activation mechanisms of the PANoptosome in autoimmune diseases remain poorly understood. Validating the structure and regulatory mechanisms of the PANoptosome in any single ...

As someone who has firsthand experience scaling a company sustainably, I have witnessed the profound impact that the organizational structure can have on long-term success. Through my experiences ...

HSBC is simplifying its organizational structure into four businesses to streamline its businesses and reduce costs months after its new chief executive took over reins. Europe's largest bank by ...

2021). Clinically, larger soft tissue defects often cause serious tissue structure damage and organ dysfunction in the oral and maxillofacial regions, which bring great disturbance to patients’ daily ...

The location of different actin-based structures is largely regulated by Rho GTPases through specific effectors. We use the apical aspect of epithelial cells as a model system to investigate how RhoA ...

Many of stars’ properties — how long they live, what color they appear, how they die — are largely determined by how massive they are. The study of stellar structure and evolution is dedicated to ...

Wnt5a signaling results in acyl protein thioesterase 1 (APT1) mediated depalmitoylation of pro-metastatic cell adhesion molecules CD44 and MCAM, resulting in increased melanoma invasion. The ...