From the Center for Systems Biology (W.C.P., M.N., F.K.S.), Massachusetts General Hospital and Harvard Medical School, Boston. From the Center for Systems Biology (W ...
Modular transcriptional repertoire analysis identified prostaglandin E 2 synthesis and signalling, leucocyte recirculation, macrophage polarisation, dectin and interleukin (IL)-1 signalling, as well ...
The dsRNA mimic IPH-3102 activates NF-κB signalling and type I IFN responses ... by LPS-binding protein (LBP), which carries LPS to the CD14 molecule, where it is then presented to the MD-2 ...
2005). Hence, boron has the potential to inhibit the inflammation process by acting at a site prior to the activation of cytokine genes in the pathway regulated by NF-kB. Anti-oxidant agents play a ...
The complex interplay between ferroptosis and efferocytosis in cancer has attracted significant interest recently. Efferocytosis, the process of eliminating apoptotic cells, is essential for ...
Hepatocellular carcinoma (HCC), the most common type of liver tumor, is a leading cause of cancer-related deaths, and the incidence of liver cancer is still increasing worldwide. Curative hepatectomy ...
Monocytes—the progenitor cell of macrophages—are classified into three types based on the expression concentrations of CD14 and CD16: classic monocytes ... which activates iron-dependent signalling ...