The last time star wide receiver Brandon Aiyuk and the San Francisco 49ers took on the Kansas City Chiefs, it did not go ...

The San Francisco 49ers' Super Bowl hangover isn't going away easily, with the Kansas City Chiefs sending them below .500 on ...

The Kansas City Chiefs own the San Francisco 49ers. Head coach Kyle Shanahan fell to 0-5 against the Chiefs and head coach ...

Kareem Hunt rushed for two first half touchdowns Sunday as the Kansas City Chiefs became the only unbeaten team in the NFL ...

Latest injury update on Brandon Aiyuk, who injured his leg and was carted off during the 49ers' game against the Chiefs on ...

Kansas City's defense ruled the day as Brock Purdy threw three interceptions and the 49ers lost Brandon Aiyuk due to injury.

The 49ers were without three of their top playmakers for much of the matchup, with running back Christian McCaffrey (Achilles ...

Former Oregon Ducks and current San Francisco 49ers defensive back Deommodore Lenoir intercepted a pass from Kansas City ...

The Kansas City Chiefs will visit the San Francisco 49ers this Sunday, Oct. 20 airing live at 4:25 p.m. ET on Fox. You can ...

A rough season for Brandon Aiyuk just got worse. The star San Francisco 49ers receiver, who held out until getting a $120 ...

San Francisco 49ers rookie receiver Ricky Pearsall made his NFL debut exactly 50 days after being shot in the chest during a ...

Latest injury update on Brandon Aiyuk, who injured his leg and was carted off during the 49ers' game against the Chiefs on ...