The last time star wide receiver Brandon Aiyuk and the San Francisco 49ers took on the Kansas City Chiefs, it did not go ...

The San Francisco 49ers' Super Bowl hangover isn't going away easily, with the Kansas City Chiefs sending them below .500 on ...

Kansas City's defense ruled the day as Brock Purdy threw three interceptions and the 49ers lost Brandon Aiyuk due to injury.

Latest injury update on Brandon Aiyuk, who injured his leg and was carted off during the 49ers' game against the Chiefs on ...

A rough season for Brandon Aiyuk just got worse. The star San Francisco 49ers receiver, who held out until getting a $120 ...

It's not looking good for the 49ers and their star receiver, so where do they go from here to save their postseason hopes?

Three-time Super Bowl MVP Patrick Mahomes has terrorized the San Francisco 49ers with two of his Vince Lombardi trophies ...

The San Francisco 49ers suffered defeat once again on Sunday, dropping a 28-18 game to the Kansas City Chiefs to fall to 3-4 ...

Notably absent from Sunday's Super Bowl rematch between the Kansas City Chiefs and the San Francisco 49ers was Taylor Swift, ...

However, Chiefs quarterback Patrick Mahomes thrives as an underdog. In 13 career starts that Kansas City was deemed the ...

Trent Williams was ejected from Sunday's game against the Chiefs.With 2:59 remaining, Chiefs safety Bryan Cook threw a punch ...

San Francisco 49ers rookie receiver Ricky Pearsall made his NFL debut exactly 50 days after being shot in the chest during a robbery attempt ...