EGFR-positive lung cancer is a type of lung cancer with an epidermal growth factor receptor (EGFR) mutation. In the United States, around 10% to 15% of lung cancers are EGFR-positive. Most of these ...

Onco360®, the nation’s leading independent Specialty Pharmacy, has been selected as a pharmacy partner by Genentech, a member ...

Distribution of different EGFR mutation statuses across the four cohorts ... Metabolism-associated hallmarks across subtypes. Gene sets for oxidative phosphorylation, peroxisome, adipogenesis, fatty ...

Tyrosine phosphorylation is an essential protein post-translational modification ... PTP1B is known as a negative regulator of several growth factor receptors such as the Epidermal Growth Factor ...

EaStCHEM School of Chemistry, The University of Edinburgh, Edinburgh EH9 3FJ, U.K. Centre for Inflammation Research, The University of Edinburgh, Edinburgh EH16 4UU, U.K. IRR Chemistry Hub, Institute ...

Membrane proteins are sorted to the plasma membrane (PM) via Golgi-dependent trafficking. However, our recent studies challenged the essentiality of Golgi in the biogenesis of specific transporters.

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Regulation of neutrophil activation plays a ...

Background and aims c-Myc is highly expressed in pancreatic multipotent progenitor cells (MPC) and in pancreatic cancer. The transition from MPC to unipotent acinar progenitors is associated with ...

Summary and Introduction Clinical Application—Disease Entities Theoretical Framework for Therapy−The 'Steel Paradigm' Conclusion References Theoretical Framework for Therapy−The 'Steel ...