Cytokine and chemokine serum levels were detected using the MILLIPLEX kit (EMD MILLIPORE) as per manufacturer’s instructions and fold changes were calculated between clodronate treated and untreated ...

In M2 macrophages ... from untreated patients (Figures 4B, C). After differentiation into M2 macrophages, the cells were treated with antibodies against the subunits of IL-4R type I (IL-4Rα; dupilumab ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Macrophages fight infection and ensure tissue ...

Department of Internal Medicine I, University Hospital, University of Regensburg, Regensburg, Germany Correspondence to: Professor Dr R H Straub Laboratory of Neuroendocrino-Immunology, Department of ...

The World Health Organization (WHO) has previously estimated that around 422 million people have diabetes, a chronic metabolic disease involving blood sugar levels, which can damage the heart, blood ...

Emapalumab is a monoclonal antibody that neutralises interferon gamma (IFN?), a key cytokine which contributes to the inflammation and ... in a session entitled "Efficacy and Safety of emapalumab in ...

25 Monocytes and macrophages can be activated through various pathways, including pattern recognition receptors responding to PAMPs and DAMPs, and stimulation by IFN-γ. 26 IL-1β is recognised as a ...

To generate in vitro derived macrophages, monocytes were isolated from healthy donors and cultured with macrophage colony-stimulating factor (M-CSF) in the presence or absence of TNFi. Cells were ...

// University of Cambridge Computer Laboratory NetFPGA team.