Oral cancer is an increasingly prevalent disease worldwide, with over 300,000 new cases diagnosed each year. Among oral ...

For the first time, researchers have used lab-grown organoids created from tumors of individuals with glioblastoma (GBM) to accurately model a patient's response to CAR T cell therapy in real time.

Tongue cancer (TC) cells can enter a chemo-resistant state by activating pathways related to autophagy and cholesterol synthesis, report researchers. Using a large-scale library of TC organoids ...

Oral cancer is an increasingly prevalent disease worldwide, with over 300,000 new cases diagnosed each year. Among oral ...

Cancer remains one of the most complex diseases, with its diverse molecular profiles and cellular compositions posing ...

Researchers frequently use organoids derived from mammary glands and tumors to study breast cancer, but they have previously been unable to generate models for the development of mammary tissue. Using ...

they built a large-scale library of tongue cancer organoids (TCOs) from surgery samples of 28 patients. Organoids are three-dimensional tissue models that mimic organs. As explained in their paper ...

Oral cancer is an increasingly prevalent disease worldwide, with over 300,000 new cases diagnosed each year. Among oral cancers, tongue cancer (TC) is ...

New study successfully made CTC-derived organoids from breast cancer patients' blood samples to investigate cell survival and ...

Tongue cancer organoid research uncovers autophagy and cholesterol pathways as key mechanisms behind chemotherapy resistance.