Many more signalling proteins are affected in cancer than transcription factors, electing transcription factors as cogent targets. One or more latent cytoplasmic transcription factors (such as ...

Since the 2023 financing round, Flare’s lead program FX-909 has moved into a phase 1 clinical trial for patients with ...

Neurobiology, Neurodegeneration and Repair Laboratory, National Eye Institute, National Institutes of Health, Bethesda, United States This important study employed multiple orthogonal techniques and ...

Flare Therapeutics Inc., a clinical-stage biotechnology company targeting transcription factors to discover precision ...

To understand the workings of DNA in relation to disease, scientists at Los Alamos National Laboratory have developed the ...

Professor Carsten Carlberg has published a comprehensive new textbook, "Gene Regulation and Epigenetics: How Science Works," ...

Michael Erb, a chemical biologist at Scripps Research and coauthor on the paper, tells C&EN that transcription factors were previously considered undruggable because they “don’t have the types ...

Discover how cutting-edge research unveiled at ACR Convergence 2024 highlights macrophage-fibroblast interactions and the ...

A representation of transcription factor proteins binding to a strand of DNA. Courtesy LANLLANL NEWS RELEASE To understand ...

Understanding how roots grow can help us develop plants that—for example—are more resistant to drought. Research by Prof.

A pivotal study has uncovered a genetic defense mechanism in lily plants against Botrytis cinerea, the fungus behind gray ...