AlphaFold solved a structural biology riddle: predicting protein structure. And yet, CASP, a global competition born to solve ...

Huntington’s disease (HD) is an inherited disorder in which the nerve cells in parts of the brain gradually break down and ...

Scientists have visualized the detailed structure of protein clumps linked to Huntington's disease, offering critical ...

Most mutations which cause disease by swapping one amino acid out for another do so by making the protein less stable, ...

Unstable proteins are the main drivers of many different heritable diseases, according to a new study, including genetic disorders responsible for the formation of cataracts, and different types of ...

Moreover, these approaches struggle with achieving the trade-off between sequence-structure consistency and diversity, making them less useful for realistic applications in exact protein design.

University of Bergen researcher Markus Miettinen is among the first scientists to provide a detailed description of protein ...

The amino acid sequence, encoded by its gene, determines a protein’s structure and function. Newly synthesized proteins can be modified by post-translational modification, altering its protein ...

Protein is vital to the functioning of cells in living organisms. Proteins are required for the structure and regulation of the body’s tissues and organs. They are made up of long chains of amino ...

P2Rank: Protein-ligand binding site prediction from protein structure based on machine learning.

The potential of using artificial intelligence in drug discovery and development has sparked both excitement and ...